Problem
Cancer prevalence is increasing, putting a strain on healthcare systems and impacting millions of lives. Traditional cancer treatments like tumor boards have limitations in time, place, and access to specialists.
Solution
Normax proposes the Educated Antigen Receptor Therapy (EARTh) GMP Process and Virtual Tumor Board(VTB) as innovative approaches to personalized cancer treatment.
EARTh GMP Process focuses on utilizing a patient’s own genetic information to develop targeted immunotherapies.
Overall, EARTh GMP Process offers a promising approach to personalized cancer immunotherapy with thepotential to improve patient outcomes and advance cancer treatment.
The Process
Patient Samples & Data
Tissue samples (healthy & cancerous) are collected from the patient with informed consent and undergo DNA sequencing.
AI-powered Analysis
Advanced AI tools process the DNA data to identify specific neoantigens (unique mutations) present inthe patient’s cancer cells.
mRNA Design & Production
The identified neoantigen sequences are used to design and print mRNA using technologies likeBioXP printer and DNA Script printer. This mRNA serves as the blueprint for personalized treatment.
Treatment Delivery
Two potential delivery methods are explored:
- Lipid Nanoparticle (LNP) Delivery: The mRNA is encapsulated in LNPs for efficient delivery into the patient. The immune response can then recognize and attack cancer cells expressing the specific neoantigens.
- Autologous Cell Transfusion Delivery: Patient’s T cells are extracted and “educated” with the mRNA outside the bodybefore being reintroduced via transfusion.
GMP Lab Testing
Before administration, the effectiveness of the personalized mRNA treatment is rigorously tested in a controlled lab environment to ensure safety and efficacy.
Benefits
Personalized Treatment
Tailored to each patient’s unique tumor profile, increasing the chances of successful treatment and minimizing side effects.
Advanced Technology
Leverages cutting-edge AI and mRNA technology for precise and efficient therapy development.
GMP Compliance
Adheres to Good Manufacturing Practices to ensure the quality and safety of the personalized treatment.
Join un in the future of AI empowered healthcare.
Contact
info@nrvx.net